What is Alzheimer’s disease?
Alzheimer’s is a progressive type of neurological disorder, defining that it can develop gradually, consequently affecting the individual’s health with more symptoms. You might have heard of brain shrinkage expression. In this condition, brain cells degenerate progressively, and the brain becomes smaller than its normal initial state. Sequential to the encounter with an Alzheimer’s patient, you will notice the worsening of intelligence, memory disorder, and recollecting the most simple daily issues. Generally, this neurological disorder can make a person incapable of conducting their behavioral skills and losing their reasonable thinking.
Primary manifestations of Alzheimer’s:
One of the most substantial approaches to treating this condition is identifying its first signs. Alzheimer’s, akin to other diseases, begins and is diagnosed by specific manifestations and symptoms. Often, people realize the momentary dementia of thoughts ready to be iterated. Furthermore, not recalling the daily events and routines is determined as another primary sign of this disease. In this stage, people mostly have difficulty saving various occurrences in their memory or serious problems confronting the patient regarding recognition and citing their thoughts.
It has occurred to all of us to comprehend our memory dysfunction in reminiscing many subjects. It also includes Alzheimer’s patients. In comparison, memory decline continues to exist in these patients, in addition to lowering the function of daily and social activities.
Behavioral and characteristical changes
One of the most conspicuous symptoms of this disease is the alteration in people’s character and rational attitude. Nevertheless, we cannot consider all types of behavioral modifications as a sign of this condition. Notwithstanding the manifestations of this disease from middle age above, one must be taken under a doctor’s surveillance once the previously mentioned signs and behavioral changes transpire. Moreover, one must conduct necessary measures for treating Alzheimer’s if obligated. Disorder people’s attitudes might involve these cases:
- Depression and seclusion
- Disorder in sleeping habits
- Behavioral fluctuations
- Lack of trust in others
- Dementia and delirium
- Creating a sense of indifference
Alzheimer’s treatment methods:
The dissipation of symptoms and Alzheimer’s treatment provides the individual to live longer next to their family members and acquaintances with more confidence, autonomy, and peace. One of the effective therapeutical methods in Alzheimer’s improvement is the use of choline esterase inhibitors. Drugs such as Memantine are inhibitors and prescribed as a treatment for these patients. These drugs have a positive role in controlling the manifestations and decreasing some of the cognitive and behavioral disorders.
One must regard that there are sundry treatment methods and pharmaceutics prescriptions from one person to another. Thereby, there is a chance of recurrence. Thus, the specialist must examine the patient’s state thoroughly and, figuratively noting, write out a suitable prescription.
Memantine prescription:
Another form of pharmacotherapy appertaining Alzheimer’s treatment is the use of the Memantine drug. It is prescribed for those in severe stages. The signs of this disease can be significantly controlled and diminished due to the assistance of this drug. Specialists have concluded that Memantine regulates the proportion of the chemical compound glutamate, furthering the preclusion of more neuron loss.
Memantine extended-release capsules have recently entered the Iran market in doses of 7, 14, 21, and 28 milligrams. In addition to better efficiency and lesser side effects compared to other Memantine pills available in the market, one can consume them once daily, which supplies comfort in consumption and patient compliance with its utility.
The table below indicates the dose change from the normal Memantine (I.R) to E.R:
Conclusion and result:
Eventually, one must refer to the essential fact that the support of family and acquaintances has a noteworthy role accompanied by Alzheimer’s treatment. These individuals require more care, thereby providing a proper situation to create comfort and convenience, immensely promoting disease control. Additionally, there is a plausibility in lessening the manifestations during the process.
References:
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Davies P, Maloney AJ. Selective loss of central cholinergic neurons in Alzheimer’s disease. Lancet 1976; 2: 1403.
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Perry EK, Gibson PH, Blessed G, et al. Neurotransmitter enzyme abnormalities in senile
dementia. Choline acetyltransferase and glutamic acid decarboxylase activities in necropsy brain tissue. J Neurol Sci 1977; 34: 247–65.
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